Archivos: Articulos

Magnesium, Little Known But Possibly Relevant: A Link between NASH and Related Comorbidities. Simón J, Delgado TC, Martinez-Cruz LA, Martínez-Chantar ML. Biomedicines. 2021 Jan 27;9(2):125. doi: 10.3390/biomedicines9020125. PMID: 33513920 Review Ver en PubMed

A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability. Nikolaeva-Koleva M, Butron L, González-Rodríguez S, Devesa I, Valente P, Serafini M, Genazzani AA, Pirali T, Ballester GF, Fernández-Carvajal A, Ferrer-Montiel A. Sci Rep. 2021 Jan 8;11(1):246. doi: 10.1038/s41598-020-80725-z. PMID: 33420359 Ver en PubMed

Cross-Talk Between the Adenylyl Cyclase/cAMP Pathway and Ca2+ Homeostasis. Sanchez-Collado J, Lopez JJ, Jardin I, Salido GM, Rosado JA. Rev Physiol Biochem Pharmacol. 2021;179:73-116. doi: 10.1007/112_2020_55. PMID: 33398503 Ver en PubMed

Melatonin downregulates TRPC6, impairing store-operated calcium entry in triple negative breast cancer cells. Jardin I, Diez-Bello R, Falcon D, Alvarado S, Regodon S, Salido GM, Smani T, Rosado JA. J Biol Chem. 2020 Dec 30;296:100254. doi: 10.1074/jbc.RA120.015769. Online ahead of print. PMID: 33380424 Ver en PubMed

PEG Equilibrium Partitioning in the α-Hemolysin Channel: Neutral Polymer Interaction with Channel Charges. Aguilella-Arzo M, Aguilella VM. Biomacromolecules. 2021 Feb 8;22(2):410-418. doi: 10.1021/acs.biomac.0c01286. Epub 2020 Dec 18. PMID: 33337868 Ver en PubMed

PGRMC1 Inhibits Progesterone-Evoked Proliferation and Ca2+ Entry Via STIM2 in MDA-MB-231 Cells. Cantonero C, Salido GM, Rosado JA, Redondo PC. Int J Mol Sci. 2020 Oct 15;21(20):7641. doi: 10.3390/ijms21207641. PMID: 33076541 Ver en PubMed

Piezo2 Mediates Low-Threshold Mechanically Evoked Pain in the Cornea. Fernández-Trillo J, Florez-Paz D, Íñigo-Portugués A, González-González O, Del Campo AG, González A, Viana F, Belmonte C, Gomis A. J Neurosci. 2020 Nov 18;40(47):8976-8993. doi: 10.1523/JNEUROSCI.0247-20.2020. Epub 2020 Oct 14. PMID: 33055278 Ver en PubMed

Investigational drugs in early phase clinical trials targeting thermotransient receptor potential (thermoTRP) channels. Fernández-Carvajal A, González-Muñiz R, Fernández-Ballester G, Ferrer-Montiel A. Expert Opin Investig Drugs. 2020 Nov;29(11):1209-1222. doi: 10.1080/13543784.2020.1825680. Epub 2020 Sep 29. PMID: 32941080 Review Ver en PubMed

Early Stimulation of TREK Channel Transcription and Activity Induced by Oxaliplatin-Dependent Cytosolic Acidification. Dionisi M, Ruffinatti FA, Riva B, Lim D, Canta A, Meregalli C, Fumagalli G, Monza L, Ferrer-Montiel A, Fernandez-Carvajal A, Cavaletti G, Genazzani AA, Distasi C. Int J Mol Sci. 2020 Sep 28;21(19):7164. doi: 10.3390/ijms21197164. PMID: 32998392 Ver en PubMed

Targeting thermoTRP ion channels: in silico preclinical approaches and opportunities. Fernández-Ballester G, Fernández-Carvajal A, Ferrer-Montiel A. Expert Opin Ther Targets. 2020 Nov;24(11):1079-1097. doi: 10.1080/14728222.2020.1820987. Epub 2020 Sep 24. PMID: 32972264 Review Ver en PubMed